Flow chamber bioreactor for medical, biotechnological and pharmaceutical uses.
MDX flow chamber bioreactor opens different and excellent possibilities for the cultivation of the functional tissues and adherent cells which need a carrier material for their growth. The fluid-bed bioreactor can be used in the medical technology and research, e.g., in the cultivation of the functioning liver cells, cartilages and flat skin cells. Moreover, it can be used in environment protection and development from drugs in pharmaceutical research. The function of MDX fluid-bed bioreactors
The fluid-bed bioreactor can be used in the medical technology and research, e.g., in the cultivation of the functioning liver cells, cartilages and flat skin cells. Some cells of the functioning tissue are removed by biopsy and are cultivated in a culture bottle with specific nutrients medium. The cells are transferred after the reproduction to the carrier pads made of polymer, of porous ceramic or fleeceon in the chamber. The cells grow to functioning tissue cultures with corresponding properties. The developed cell cultures are removed enzymatic and further processed. The tissue cultivation process is carried out in an incubator at optimal temperature. The required nutrient medium for the cultivation of cell tissue must be prepared outside the fluid bed chamber. It is enriched with necessary nutrients for growth of the cells. The nutritious medium is pumped by a peristaltic pump continuous and slowly to the cells in the fluid-bed chamber. The spent medium is to remove by means of a pump from the chamber. The aeration of the cells is directly by convection. On this way, the tissues and the cells are optimally supplied with oxygen and nutrients and can grow well. The fluid-bed bioreactor can be used also in cell cultivation for the production of eukaryotic proteins, monoclonal antibodies and other cell substances of research and pharmaceutical industry and with specific bacteria’s in the preliminary examinations and tests of the biotechnology e.g. at the reduction of pollutions in the wastewater or in the ground.
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